Bracken fiddleheads have been considered edible by many cultures throughout history, and are still commonly used today as a foodstuff. Bracken fiddleheads are either consumed fresh or preserved by salting, pickling, or sun drying. In Korea, where they are called gosari ,they are a typical ingredient in the mixed rice dish called bibimbap.

Both fronds and rhizomes have been used to brew beer, and the rhizome starch has been used as a substitute for arrowroot. Bread can be made out of dried and powered rhizomes alone or with other flour. American Indians cooked the rhizomes, then peeled and ate them or pounded the starchy fiber into flour. In Japan, starch from the rhizomes is used to make confections.

Bracken is called wiwnunmí útpas ‘huckleberry’s blanket’ by the Umatilla Indians of the Columbia River in the United States Northwest. The fronds were used to cover a basket full of huckleberries in order to keep them fresh.

The Māori of New Zealand used the rhizomes of P. Esculentum as a staple food, especially for exploring or hunting groups away from permanent settlements; much of the widespread distribution of this species in present-day New Zealand is in fact a consequence of prehistoric deforestation and subsequent tending of aruhe stands on rich soils. The rhizomes were air-dried so that they could be stored and became lighter; for consumption, they were briefly heated and then softened with a patu aruhe; the starch could then be sucked from the fibers by each diner, or collected if it were to be prepared for a larger feast. Patu aruhe were significant items and several distinct styles were developed.

Bracken has also been used as a form of herbal remedy. Powdered rhizome has been considered particularly effective against parasitic worms. American Indians ate raw rhizomes as a remedy for bronchitis.

In East Asia, Pteridium aquilinum is eaten as a vegetable, called warabi in Japan, gosari in Korea, and juécài in China and Taiwan. In Korea, a typical banchan is gosari-namul that consists of prepared fernbrake that has been sauteed. It is a component of the popular dish bibimbap.

Bracken has been shown to be carcinogenic in some animals and is thought to be an important cause of the high incidence of stomach cancer in Japan. It is currently under investigation as a possible source of new insecticides.

Uncooked bracken contains the enzyme thiaminase, which breaks down thiamine. Eating excessive quantities of bracken can cause beriberi, especially in creatures with simple stomachs. Ruminants are less vulnerable because they synthesize thiamine.

It was traditionally used for animal bedding, which later broke down to a rich mulch which could be used as fertiliser.

When used by gardeners as a winter mulch it has been shown to reduce the loss of Potassium and Nitrogen and to lower soil PH.

Other uses were as packing material for products such as earthenware, as a fuel, as a form of thatch. The ash was used for degreasing woolen cloth.

The ash of bracken fern was used in making forest glass in Central Europe from about 1000 to 1700.

Bracken is currently harvested in the Lake District, Cumbria, United Kingdom to make commercial composts.